Skin Hydration Assay

Investigating hydration levels and anti-aging processes through in vitro testing is crucial for developing targeted and effective treatments, providing a more controlled and reliable environment than traditional approaches.

Purpose of the Test

The MIVO-based skin hydration test utilizes the MIVO® skin-on-chip platform and optimized protocols for resembling dehydarated skin in vitro to evaluate effectiveness of treatments on skin hydration, focusing on proper hydratation tissue level restoration.

The MIVO^® Advantage: A Superior Predictive Model

MIVO® technology offers a dual advantage: (i) it enables to resemble different skin hydration levels, simulating various aging stages, and (ii) improves long-term skin tissue viability through dynamic fluid flow, mimicking real physiological conditions. This innovative approach provides a deeper insight into hydration mechanisms and anti-aging effects, surpassing visual or self-assessed clinical tests and delivering a superior solution for skin care evaluations.

Our Unique Value Proposition

Realistic, 3D, Humanized tissue Model: The MIVO® platform integrates a 3D RhE with dynamic fluid flow, simulating real-life skin conditions more effectively than static systems. This enhanced physiological accuracy allows for a more precise prediction of hydration and anti-aging effects.

Mechanism-Based Insights: Beyond basic visual assessments or self-reported clinical data, the MIVO® based assay allows for a deeper investigation into the biological mechanisms behind skin hydration and aging. By analyzing cellular responses in detail, this test provides a comprehensive and semiquantitative understanding of how treatments impact the skin at a molecular level.

Superior Precision: The dynamic fluid flow within the MIVO® platform closely mimics the movement of nutrients and water in real skin, allowing for precise measurements of hydration and elasticity. This assay enables accurate, real-time assessments of how treatments perform under physiological conditions, helping to highlight their benefits.

Throughput: the platform enables to carry out simultaneusly up to 12 independent experiments, supporting multiples doses evaluation of the testing compounds, and evaluating their effect on different aging state of the skin.