Enhancing Predictive Power in Human Intestinal Research with Advanced Gut-on-Chip Technology

The human gut is a complex and dynamic ecosystem essential for digestion, drug absorption, and overall health. However, traditional in vitro and animal models struggle to accurately replicate its intricate processes. In this webinar, we introduce a revolutionary multicompartmental gut-on-chip model, powered by the innovative MIVO® millifluidic device, designed to faithfully simulate the human intestinal environment with unprecedented precision.
Through the co-culture of human intestinal Caco-2 and HT-29 cells under fluid dynamic conditions, we replicate the complexities of the human bloodstream, achieving a functional and differentiated intestinal barrier within just 7-10 days—less than half the time required by conventional static cultures. This advanced model also incorporates a dual apical-basal flow system, enabling the formation of three-dimensional structures and mimicking the intestinal permeability observed in vivo.
Interestingly, this innovative approach also provides precise control over mucus thickness and barrier integrity—crucial parameters for studying intestinal diseases, drug absorption, and the intricate interactions between host and microbiota.
This cutting-edge technology redefines the standard for in vitro testing, offering unparalleled accuracy and predictive power for drug development, nutraceutical research, and the study of intestinal diseases.
Join us to explore how this next-generation platform can elevate your research and development capabilities, delivering results that faithfully replicate human physiology and expand the horizons of modern science.